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A lipid droplet-targeted Pt(ii) complex enables photoinduced ferroptosis and apoptosis against cisplatin-resistant cells 期刊论文

编号：

A8D9DD31D403869B4302BBBD337EDDE7
作者：

Hui, Puzhen#^[1]Xu, Fengwu^[2];Zheng, Huilin^[1];Yao, Shankun*^[2]Chen, Yuncong*^[2]Gu, Xiaoxia(谷晓霞)*^[1]Guo, Zijian^[2];
语种：

英文
期刊：

CHEMICAL COMMUNICATIONS ISSN：1359-7345 2026 年 ; 2026 FEB 27
收录：
摘要：

The development of metal complex-based photosensitizers that can precisely regulate cell fate via lipid droplet (LD)-mediated pathways remains challenging. Herein, an LD-specific targeting Pt(ii) complex was designed to address this limitation by directly inducing sufficient lipid peroxidation (LPO) accumulation, offering a novel platform for synergistic ferroptosis-apoptosis cancer therapy. This work provides a novel anticancer platform using photoactivated platinum complexes to concurrently trigger dual cell death pathways.
推荐引用方式
GB/T 7714：

Hui Puzhen,Xu Fengwu,Zheng Huilin, et al. A lipid droplet-targeted Pt(ii) complex enables photoinduced ferroptosis and apoptosis against cisplatin-resistant cells [J].CHEMICAL COMMUNICATIONS,2026.
APA：

Hui Puzhen,Xu Fengwu,Zheng Huilin,Yao Shankun,&Guo Zijian.(2026).A lipid droplet-targeted Pt(ii) complex enables photoinduced ferroptosis and apoptosis against cisplatin-resistant cells .CHEMICAL COMMUNICATIONS.
MLA：

Hui Puzhen, et al. "A lipid droplet-targeted Pt(ii) complex enables photoinduced ferroptosis and apoptosis against cisplatin-resistant cells" .CHEMICAL COMMUNICATIONS(2026).
入库时间：

3/17/2026 10:00:27 PM
更新时间：

3/17/2026 10:00:27 PM

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